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Methodological context for: Travell J, Rinzler SH, Bakst H, Benjamin ZH, Bobb AL (1949). Comparison of effects of alpha-tocopherol and matching placebo on chest pain in patients with heart disease. Annals of the New York Academy of Sciences 52:345-53.
- Allocation bias
- Differences between the people compared
- Observer bias
- Differences in the way treatment outcomes are assessed